Enzyme inhibition, and which line moves
Maya, Dev and Ava wrote this, Tuesday
Competitive inhibitors bind the active site. Km rises, Vmax is unchanged, and enough substrate outcompetes them.
Non competitive inhibitors bind somewhere else on the enzyme. Vmax falls, Km is unchanged, and more substrate does not rescue it.
Only Ava wrote this down
On a Lineweaver-Burk plot, competitive moves the x intercept and non competitive moves the y intercept. That is the graph question every year.
Still open. Dev asked whether substrate ever rescues non competitive inhibition. Nobody has answered yet, so it stays on the note.
